Biowarfare can now be considered 5th generation warfare and
is becoming lethal day by day. this is often a voiceless menace, more dangerous
than nuclear warfare because the use of biological toxins or infectious agents
like bacteria, viruses, insects, and fungi with the intent to kill or
incapacitate humans, animals or plants is an act of war. Biological weapons
live organisms or replicating entities (viruses, which aren't universally
considered “alive”). Biological weapons could also be employed in various ways
to realize a strategic or tactical advantage over the enemy, either by threats
or by actual deployments. This virus could also be lethal or non-lethal and
should be targeted against one individual, a gaggle of individuals , or maybe a
whole population but unfortunately, contantion movie coronavirusit paralyses society. they'll be developed,
acquired, stockpiled or deployed by nation-states or by non-national groups.
within the latter case, or if a nation-state uses it clandestinely, it's going
to even be considered bioterrorism. This biowarfare is undoubtedly a weapon of
war that acts mercilessly and even icreator doesn't begin unscathed.
We are experiencing this today, with the coronavirus which
comes from an outsized family of viruses that cause illness starting from the
cold to more severe diseases like Middle East Respiratory Syndrome (MERS-CoV)
and Severe contantion movie coronavirus Acute Respiratory Syndrome (SARS-CoV). It acts fast and multiplies
its victims in no time . it's a live virus and is now proving to be very
dangerous for people and even states are seen to be helpless in its face. the
large question is about where it came from, where patient zero is, is that this
difficult to trace and most significantly , was it reported from China, Italy
or Iran first? The blame game between China and therefore the USA has already
started as each side have strong points and if it's not investigated then this
blame won't come to an end. I even have little question in my mind that it's
either man-made or naturally grown and hence we'd like to delve into the small
print to clear this matter out completely. the planet wants to understand the
facts and that i propose that a high powered commission is constituted through
the UN and therefore the WHO to research with TORs. These should include, the
precise bioanalysis of Coronavirus (COVID-19), its origin and find the primary
victim, which is extremely important to trace the origin of this virus. Another
factor that must be investigated is regarding the biological changes that
happen when the virus enters the physical body . Additionally, does the
coronavirus bring an equivalent biological changes or vary from human to human?
The bird flu was detected in time and an antidote was found; allow us to see if
there was any previous research available with some states as this is often
reported to be from the family of viral flu.
The novel coronavirus (nCoV) may be a new strain that has
not been previously identified in humans. Several known coronaviruses are
circulating in animals that haven't yet infected humans which are inbuilt the
system within the physical body . i feel the assistance from veterinary experts
could also be ready to help with this issue. allow us to discuss some man-made
biological weapons supported the deadly virus.
ISLAMABAD: Genetic simplicity and defective replication
machinery ofcontantion movie coronavirus viruses make them masters of adjusting forms and these
successively cause failure of our diagnostic and therapeutic strategies.
The ‘gene pools’ of viruses change over time by
recombination or random mutations giving rise to new viral strains with different
properties.
To understand how viruses evolve, the 2009 H1N1 swine
influenza pandemic caused by Influenza virus offers a classic example of
Influenza virus evolution by recombination. When two influenza viruses infect
the same cell at the same time, variety of the new viruses made inside the cell
may have a mix of genetic segments thus exhibiting different properties. Pigs
are ‘mixing vessels’ for influenza viruses. Apart from the Pig Influenza virus,
the pig cells are often infected with the human and birds Influenza viruses at
the same time. At a given time, if a cell is infected with two different
Influenza viruses, the newly formed progeny of viruses would have a mix of
genetic material. Scientists acknowledged that H1N1 Influenza virus had genetic
segments from human, birds and pigs viruses involved together in steps which
could have taken years. SARS CoV-2 – commonly mentioned because the novel
coronavirus – responsible for Covid-19, is that the seventh coronavirus to
infect citizenry .
Previously, the SARS epidemic of 2003 and MERS outbreak in
2014 are well documented.
Being an RNA virus-like SARS and MERS coronaviruses which
originated in bats, CoV-2 also has originated in bats and is extremely
vulnerable to mutations thus evolving rapidly.
The rate of evolution of CoV-2 is being assessed but still,
the initial assessment indicates that as compared to SARS, it evolves slowly.
However different polymorphisms in strains isolated from
China, Italy and USA indicate that it can accumulate 2 to 3 mutations per month
which suggests that it will still challenge our control strategies in future
and possesses the potential to re-emerge too.
The emergence of novel and variant viruses from the wild
animals has been predicted by scientists, particularly after the SARS outbreak.
this outbreak started in November 2019 in China and within 2
months the infection reached 146 countries. What makes CoV-2 because the
foremost dangerous pathogen is that the straightforward transmission and its
severe complications which are like SARS and MERS. Epidemiologists have
estimated that if the virus weren't contained, it can infect half the earth
population during a matter of a month.
Globalisation has challenged our control strategies for
infectious diseases.
the rise of free social media platforms within the worldwide
world has intensified the flow of knowledge and propaganda at the same time.
Conspiracy theories are always very thrilling because these aren't on the brink
of reality. As soon because the CoV-2 outbreak started, the conspiracy
theorists started their job to return up with alternative explanations mainly
that concentrate on the power struggle between China and thus the US. As the
state of affairs between the two countries is documented around the globe,
conspiracy theorists started connecting the dots so on prove that CoV-2 was a
man-made pathogen which was engineered within the US to specialise in China.
People in power and politics usually do propaganda because it suits them to
influence public opinion but scientists are always trying to seek out facts.
Several scientific investigations in January and February indicated that CoV-2
isn't new in entirety which similar coronaviruses are characterised long before
from different animal species also as citizenry . A study by Chinese scientists
analysed quite 100 genomic sequences of CoV-2 in conjunction with other
coronaviruses and located out that its genomic sequence was 96% almost like
coronavirus of Bats origin indicating without a doubt that it originated in
bats a touch like MERS and SARS. However, they found variations within the
Spike gene between CoV-2 and Bat Co-V. Spike protein binds with human receptor
ACE2 and is taken under consideration as most significant for its virulence.
Here some people started speculations that probably the spike gene was
introduced into Bat Co-V within the lab so on form the foremost virulent CoV-2.
However, other scientists thoroughly analysed the sequencing data for locating
any evidence of genetic manipulation in CoV-2 but they failed. A recent
scientific investigation led by Kristian G Andersen of the Scripps Institute
conclusively proved that the Spike gene of CoV-2 has resulted from survival and
evolution which there's no evidence of it being manipulated by techniques of
gene-splicing . The investigators rejected the thought on two grounds: 1. If
the strain had been manipulated using any of the known techniques in
gene-splicing , there would are left over traceable elements of the systems
used which during this case are none. 2. The binding domains of the Spike genes
and their affinity to bind strongly to the human ACE2 receptors were previously
unknown, although only recent studies identified a uniform Spike gene in
Pangolin Coronavirus with same binding domains but its binding affinity studies
haven't been performed before. It is therefore impossible that CoV-2 has been
manipulated in any way.
The study further highlighted several possible scenarios for
the viral evolution including animal to human, human to human and accidental
escape of mutants from cell cultures in BCL1/2 labs.
0 comments: